Prostate cancer, is curable when detected well in time. Survival is often over decades. With newer treatment options coming in, there is now hope for last stage prostate cancer.
Nicknamed magic bullet therapy, now targeted alpha therapy offers hope for even metastasized, castration resistant prostate cancer( mCRPC and has changed the way metastatic prostate cancer can now be treated.
How does Magic Bullet Therapy work for Prostate Cancer ?
Prostate-specific membrane antigen radiology ( PSMA-RLT) with 177 Lu, holds great potential as the Prostate Specific Member antigen peptide binds itself specifically to prostate cancer cells but not to normal healthy cells. With a range of 0.1mm, this method allows selective irradiation, killing cancerous cells with minimal damage to healthy tissue.
The Alpha emitters work by inducing clusters of DNA damage such as double- stranded breaks and cellular cell modifications which leads to destruction of cancerous cells due to cell cycle arrest.
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What are the long term implications of holding your pee ?
Most of us often end up, holding going to the washroom off and on. But do we realise, the long term damage that happens in the process ?
When we feel the urge to urinate, the process involves coordination between muscles, organs and nerves.
When your bladder is half full, it activates the nerves in your bladder which then signal your brain to give you the urge to urinate. The brain then signals the bladder to hold on. Holding your pee for long involves consciously fighting the brain signal to urinate.
When we hold on to the pee for long, the urine can back flow into the ureter into the kidneys and lead to a urinary tract infection in the bladder or the urethra. The infection can then travel to the kidney and lead to kidney infection and even kidney disease.
When treated in time, simple antibiotics can cure UTI’s.
Untreated bladder infections may lead to more severe problems such as bacterial blood stream infections which may cause sepsis, also kidney disorders and subsequent damage which over time may lead to dialysis followed by kidney transplant.
Holding pee for long also weakens the bladder muscles and leads to urinary retention, where the bladder doesn’t get emptied and one has to urinate very often.
Other problems include enlarged prostate, weak pelvic muscles, inflammation of the bladder walls, pain in lower abdomen which does not go away, incontinence and kidney failure.
To get a 2 opinion on your kidney and urinary problems, Consult now