Cancer of Connective tissue is known as Soft Tissue Sarcoma. It includes various tissues of the body including muscle, fat, and fibrous tissue. The most common sarcomas in children are Rhabdomyosarcoma (muscle), Osteosarcoma (bone cells), and Ewing Sarcoma (in or outside of bone). However, about there are more than 50 other types of soft tissue sarcomas that affect around 900 children each year
Soft Tissue Sarcomas is further categorized as following:
1. Synovial sarcoma
2. Malignant peripheral nerve sheath tumor
3. Embryonal sarcoma of the liver
4. Desmoplastic round cell tumor
5. Desmoid tumors
6. Rhabdoid tumors
7. Epithelioid sarcoma
9. Alveolar soft part sarcoma
11. Undifferentiated Sarcoma
The “Ewing family of tumors” includes Ewing sarcoma, atypical Ewing sarcoma, and peripheral primitive neuroectodermal (PNET) of bone or soft tissue, and they are all treated in the same manner.
A nonheritable chromosomal mutation can be identified in the tumor cells of the Ewing family of tumors.
The cause of Ewing family of tumors is not yet known but it is believed this mutation plays an important role. It is second most common bone cancer is Ewing sarcoma in children.
It effects mainly long bones of arms and legs, the skull, spin, chest wall and the pelvis. It can also effect the soft tissue devoid of bone.
This disease most often occurs in adolescents, with nearly half of cases arising between the ages of 10 and 20. It is somewhat more common in males than in females.
Ewing sarcoma Symptoms:
Signs and Symptoms include pain and swelling, loss of appetite, fever, malaise, fatigue, weight loss, back pain and “sciatic–like” symptoms in patients with tumors in the pelvis.
Treatment of Ewing sarcoma:
Treatment for Ewing sarcoma include chemotherapy, surgery and targeted radiotherapy which focused at 3D-conformal radiation therapy and Intensity-modulated radiotherapy.
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Lump of sick cells stuck together develop solid tumor called Solid Sarcomas. It can develop in many parts of the body including the brain, kidneys, liver and bones.
These sick cells crowd out healthy cells.
Common types of solid tumor cancers include:
- Ewing sarcoma
- Wilms tumors.
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