Second most common solid tumor is Neuroblastoma in childhood, which affecting about 7% of all children with cancer. It is also very common solid cancer in infants as well.
There are over 700 cases each year in the U.S. Neuroblastoma generally originates in the adrenal glands (which are located on top of each kidney). However, tumors can begin anywhere in the body including chest, neck and pelvis. The cells that make up neuroblastoma tumors are called neuroblasts.
In this type of cancer, the neuroblasts grow and divide without the usual growth checkpoints and controls, leading to the growth of a cancerous mass of cells known as tumor.
Signs and Symptoms consist of Abdominal swelling, pain, Constipation, Difficulty in urination if a tumor is present in the abdomen.
A lump or bump in the neck that can sometimes be accompanied by drooping of the eyelid, a small pupil, and lack of sweating on the same side of the face, Bone pain, Fatigue, Bleeding and bruising, Fever, Difficulty breathing if the tumor is present in the chest, Weakness or paralysis, High blood pressure, Rapid heartbeat and Persistent diarrhea
Treatment of Neuroblastoma:
Treatment options for Neuroblastoma are surgery, chemotherapy, Radiation therapy, Stem cell transplantation/bone marrow transplantation, Retinoid therapy and Immunotherapy.