Prostate cancer, is curable when detected well in time. Survival is often over decades. With newer treatment options coming in, there is now hope for last stage prostate cancer.
Nicknamed magic bullet therapy, now targeted alpha therapy offers hope for even metastasized, castration resistant prostate cancer( mCRPC and has changed the way metastatic prostate cancer can now be treated.
How does Magic Bullet Therapy work for Prostate Cancer ?
Prostate-specific membrane antigen radiology ( PSMA-RLT) with 177 Lu, holds great potential as the Prostate Specific Member antigen peptide binds itself specifically to prostate cancer cells but not to normal healthy cells. With a range of 0.1mm, this method allows selective irradiation, killing cancerous cells with minimal damage to healthy tissue.
The Alpha emitters work by inducing clusters of DNA damage such as double- stranded breaks and cellular cell modifications which leads to destruction of cancerous cells due to cell cycle arrest.
To know more about Targeted Alpha Therapy for Prostate Cancer, send us an email on firstname.lastname@example.org or click to send us a query.
The PET CT Scan is one of the sought after diagnostic tests. Let’s find out more about what is a PET CT and why is it preferred over other diagnostic tests, such as an MRI, CT Scan or an ultrasound.
What is a PET Scan?
A PET Scan is a nuclear medicine technique which produces images of the human body at a molecular level.
A PET CT uses radioactive tracers in conjugation with isotopes such as oxygen, nitrogen, carbon etc. These radioisotopes act at a molecular level and work as probes which seek out disease, cancer in the body while giving out radio signals which are captured to produce an image.
This can help in the diagnosis of even the tiniest lesions, thus increasing the accuracy of the investigation, subsequent diagnosis and hence cancer treatment.
A PET CT Scan, therefore reveals a lot more about the body than standard diagnostic tests such as MRI, CT Scan or an ultrasound.
What happens during a PET Scan?
A PET CT Scan, is always on a price appointment basis as the radioisotopes, having a very short half-life need to be brought in just before the scan.
A PET CT, is usually carried out empty stomach on overnight or at least 6 hrs fasting.
The creatinine levels, need to checked prior to conducting the PET CT by simple blood tests called KFT or Kidney function test
If the creatinine levels are in order, the patient is tested for blood sugar and if found in order, the patient is given an injection of glucose with a radioactive tracer.
After the injection, the patient is made to rest for about 90 mins and then taken for the actual scan which takes about 30 mins to 45 mins depending on the imaging required.
During the scan, the patient is made to lie on a comfortable table that moves slowly through the ring like PET scanner.
After the scan, the patient can leave immediately. However close contact with others especially children and pregnant women is best avoided for the next 4-6 hrs.
It is also good to drink a lot of water, to flush out the radioactive tracer from the body.
The imaging can be seen by the doctors and the nuclear medicine specialists almost immediately for evaluation, though a formal written report takes a day to be handed over to the patient.
Are there any side effects or discomfort due to the scan?
There are no side effects or discomfort due to the PET CT Scan, except the minor prick while injecting the tracer.
The PET CT scanner also does not make any sounds while the scan is going on, unlike a few other diagnostics tests.
What are the diseases for which a PET CT Scan can be used?
The most common use case for a PET CT Scan is for detecting and treating cancer. However other applications, include diagnosing cardiac or heart problems and also neurology.
During the initial stages of the disease, a PET CT helps distinguish between benign and malignant disease and also cancer staging, that is knowing and determining the stage of the disease and also its characteristics, which further helps oncologists decide the best treatment option for the patient.
During the course of treatment, it helps determine response to therapy or cancer treatment and if the metabolic activity decreases on the PET CT Scan, the oncologists know that the drugs being administered are working.
On the other hand, if the metabolic activity on the scan increases, it indicates that the treatment option is losing its efficacy or is not working and helps oncologists change the line of treatment to benefit the patient.
Neurology: Alzheimer’s at an early stage can be diagnosed using a PET Scan leading to early intervention.
A PET CT Scan helps locate tumors, distinguish between benign and malignant tumors and also scar tissue for brain surgery.
A PET CT is also useful for the treatment of epileptic seizures. It can help locate the origin and focus of seizures and assess sites for intervention if any is required.
What is the difference between a PET CT and an MRI or a CT ?
A CT or an MRI works on the physical level and can give the size and location of the tumor with accuracy.
However since both tests do not work on the molecular level, they cannot indicate metabolic activity of the tumor which only a PET CT Scan can indicate, thereby making a PET CT, a diagnostic test of choice for oncologists, cardiologists, cardiac or heart surgeons and interventional neurologists.
To know more about, PET CT Scans, cost, and implications, from the best cancer hospitals in India, write to us on email@example.com or send us a query.
Infertility is defined as inability to conceive or carry a pregnancy to full term.
Infertility affects millions of women worldwide. IVF or assisted In vitro fertilisation is the answer to infertility problems for millions of women, unable to conceive naturally or carry a pregnancy full term.
We receive several queries on a daily basis on IVF. Here’s an attempt to answer the common questions on IVF treatment.
Q.When do I explore, IVF as an option for conception ?
Ans. If you are not able to conceive for an 1 year after unprotected intercourse is when IVF should be explored.
Q.How long does IVF treatment last ?
Ans. A successful IVF may need one cycle or a couple more cycles. Each IVF cycle takes 4-6 weeks to complete.
Q.What if I am ok but my husband is found sterile or has a very low sperm count?
Ans. In such a case donor sperms may be used. Please write to us for more information on firstname.lastname@example.org or click here to send us a query.
Q.What will happen if the quality of my own eggs is poor ?
Ans. If the quality of eggs is really poor, IVF can be carried out using donor eggs also, incase there is no other viable alternative.
Q.What I have fibroids ? Do they interfere with conception ?
Ans. Fibroids interfere with conception and are usually removed by laparoscopic fibroid surgery or myomectomy for better results.
To know cost of myomectomy, please email us on email@example.com or click here to send us a query.
Q. What if I have endometriosis ?
Ans. If you have an endometriotic cyst, it can be removed with laparoscopic surgery before you ahead with IVF treatment.
Q. What if I have had failed cycles of IVF already ?
Ans. ICSI, laser hatching, Embryoscope and IMSI are some of the options which give better results.
To know more on IVF treatment, or to get a 2nd medical opinion on your health problem, send us a query or write to us on firstname.lastname@example.org.
Childhood cancers or Paediatric cancers are biologically different from adult cancers.
They grow faster than most adult cancers.
Factors which trigger cancer or cause childhood cancers are different from those causing adult cancers for example smoking a leading cause of adult lung cancer is not a cause for childhood lung cancer.
Most Paediatric cancers are non hereditary and happen due genetic mutations of growing up cells, though pollution, exposure to radiation, chemicals are also contributory factors in a few cases.
Common cancers in children:
The most common childhood cancer is Leukemia or Blood Cancer. Of all types of blood cancers, ALL is the most common one. It affects children in the age group of 2-6 years.
Other common paediatric cancers are tumours of the brain, retinoblastoma, neuroblastoma, lymphoma, tumours of the kidney, tumours of the adrenal gland, sarcomas , bone tumours etc.
Symptoms of Childhood Cancers:
Unusually High Fever
Bruise marks or blue marks on the body
Prolonged fever with no established cause
Unusual weight loss
Nose bleed, gum bleed
Swelling in the abdomen
Pale palor, accompanied with fever, body ache
Swelling in the neck or axilla.
Increase in size of lymph nodes, along with cough, fever, weight loss
Unusual Redness in the eye
Early morning vomiting, loss of appetite
If you notice any of these, it may be a good idea to plan a visit to the doctor.
Are Childhood cancers curable ?
As childhood cancers grow faster than adult cancers, they are also more responsive to chemotherapy and other forms of treatment.
Depending on the stage of cancer and the spread of cancer, a combination of surgery, chemotherapy and radiation may be advised.
With advances in medical treatment, it is now possible to save limbs in bone cancers, eyes in retinoblastoma depending upon stage of cancer and response to treatment options.
Most blood cancers in children respond extremely well to chemotherapy and get cured.